BACKGROUND: The global tuberculosis epidemic results in nearly 2 million deaths and 9 million new cases of the disease a year.The vast majority of tuberculosis patients live in developing countries, where the diagnosis of tuberculosis relies on the identification of acid-fast bacilli on unprocessed sputum smears using conventional light microscopy.
Ecological niche of plant pathogens
Disease ecology is a new approach to the understanding of the spread and dynamics of pathogens in natural and man-made environments.Defining and describing the ecological niche of the pathogens is one of the major tasks for ecological theory, as well as for practitioners preoccupied with the control and forecasting of established and emerging disea
Pandemic influenza control in Europe and the constraints resulting from incoherent public health laws
Abstract Background With the emergence of influenza H1N1v the world is facing its first 21st century global pandemic.Severe Acute Respiratory Syndrome (SARS) and avian influenza H5N1 prompted development of pandemic preparedness plans.National systems of public health law are essential for public health stewardship and for the implementation of pub
The Adenovirus Vector Platform: Novel Insights into Rational Vector Design and Lessons Learned from the COVID-19 Vaccine
The adenovirus vector platform remains one of the most efficient toolboxes for generation of transfer vehicles used in gene therapy and virotherapy to treat tumors, as well as vaccines to protect from infectious diseases.The adenovirus genome and capsids can be modified using highly efficient techniques, and vectors can be produced at high titers,